无烟烟草戒除群组随机试验:农村高中男生;干预与基线吸烟的相互作用。
Smokeless tobacco cessation cluster randomized trial with rural high school males: intervention interaction with baseline smoking.
机构信息
Department of Preventive and Restorative Dental Sciences, School of Dentistry, University of California, San Francisco, CA 94143-1361, USA.
出版信息
Nicotine Tob Res. 2010 Jun;12(6):543-50. doi: 10.1093/ntr/ntq022. Epub 2010 May 3.
INTRODUCTION
Adolescent males in rural areas use smokeless tobacco (ST). We assessed the efficacy of a school-based nurse-directed ST intervention among rural high school males.
METHODS
Study high schools were randomly selected from a public high school list of California rural counties. Consenting high schools were stratified by school size and randomly assigned within strata to intervention or no-intervention groups. After gaining parental consent, male students completed baseline and 1-year follow-up questionnaires. The intervention included peer-led educational sessions and an oral exam by the school nurse who also provided brief tobacco cessation counseling. We used binary generalized estimating equation (GEE) models accounting for clustering within schools to test no difference between groups after adjusting for year in high school using both completers only and multiple imputation for those lost to follow-up. Subgroup analyses assessed Baseline Factor x Group interaction in GEE models.
RESULTS
Twenty-one rural counties (72%), 41 randomly selected high schools (56%), and 4,731 male students (50%) participated with 65% retention. Nonsmoking ST users in the intervention group were significantly more likely to stop using ST at follow-up than those in the no-intervention group; there was no intervention effect among baseline ST users who also smoked. A higher percentage of baseline nonsmoking ST users reported smoking at follow-up than baseline non-ST-using smokers who reported using ST.
DISCUSSION
A school-based nurse-directed ST cessation program was efficacious among rural nonsmoking ST-using high school males. The potential program reach holds significant public health value. Baseline ST use facilitated smoking at follow-up.
简介
农村地区的青少年男性使用无烟烟草(ST)。我们评估了基于学校的护士指导的 ST 干预对农村高中男性的效果。
方法
从加利福尼亚农村县的公立高中名单中随机选择研究高中。同意的高中按学校规模分层,并在分层内随机分配到干预组或无干预组。在获得家长同意后,男学生完成基线和 1 年随访问卷。干预措施包括由同伴领导的教育课程和学校护士进行的口腔检查,护士还提供简短的烟草戒断咨询。我们使用二元广义估计方程(GEE)模型,根据学校内的聚类来测试在调整高中年级后,两组之间没有差异,同时仅使用完成者和对随访丢失者进行多重插补进行分析。亚组分析评估了 GEE 模型中基线因素 x 组交互作用。
结果
21 个农村县(72%)、41 所随机选择的高中(56%)和 4731 名男学生(50%)参与了研究,其中 65%的学生保留了下来。与无干预组相比,干预组中基线不吸烟的 ST 用户在随访时更有可能停止使用 ST;基线吸烟的 ST 用户没有干预效果。与基线不使用 ST 的吸烟者报告使用 ST 的人相比,更多的基线不吸烟的 ST 用户报告在随访时吸烟。
讨论
基于学校的护士指导的 ST 戒烟计划对农村不吸烟的 ST 使用高中男性有效。潜在的项目覆盖面具有重要的公共卫生价值。基线 ST 使用促进了随访时的吸烟。