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墨尔本视力损害项目中白内障的发病率及进展情况

Incidence and progression of cataract in the Melbourne Visual Impairment Project.

作者信息

McCarty Catherine Anne, Mukesh Bickol Nanjan, Dimitrov Peter N, Taylor Hugh Ringland

机构信息

Marshfield Medical Research Foundation , Marshfield Clinic, Marshfield, Wisconsin, USA.

出版信息

Am J Ophthalmol. 2003 Jul;136(1):10-7. doi: 10.1016/s0002-9394(02)01844-5.

Abstract

PURPOSE

To determine the 5-year incidence and progression of cataract and cataract surgery in the Melbourne Visual Impairment Project.

DESIGN

Prospective cohort study. methods: Demographic information including race, sex, age, and education level was collected at baseline. Cortical cataract was defined as 4/16 or greater opacity; progression was defined as a more than 2/16 increase. Nuclear cataract was defined as Wilmer standard grade 2 or higher; progression was defined as more than 0.5 increase. Posterior subcapsular (PSC) cataract was defined as opacity 1 mm(2) or greater; progression was defined as greater than 1 mm(2) increase. results: Of the 3040 participants eligible to attend follow-up examinations, 2594 (85% of those eligible) participated. The mean age of participants at follow-up was 62.5 years, and 55% were female. The percentage of patients who had at least one lens extracted over 5 years increased from 0.5% of those aged 40 to 49 years at baseline to 35.7% of those aged 80 years or more at baseline. The overall incidence of the three types of cataract was as follows: cortical 7.7% (95% confidence limits [CL] = 5.8-9.8), nuclear 16.4% (95% CL = 12.1-20.8), and PSC 7% (95% CL = 5.3-8.7). The overall progression of cataract was cortical 14.3% (95% CL = 10.2-18.3), nuclear 19.3% (95% CL = 15.9-22.7), and PSC 20% (95% CL = 8.7-31.1). The incidence and progression rates increased significantly by age, but the rates were not significantly different by sex.

CONCLUSION

These cataract incidence data confirm the public health importance of cataract in Australia. The data also support the need to plan both primary prevention program and adequate surgical services to meet the anticipated increase in demand with the aging population.

摘要

目的

在墨尔本视力损害项目中确定白内障的5年发病率及进展情况以及白内障手术情况。

设计

前瞻性队列研究。

方法

在基线时收集包括种族、性别、年龄和教育水平在内的人口统计学信息。皮质性白内障定义为混浊度达到4/16或更高;进展定义为增加超过2/16。核性白内障定义为威尔默标准2级或更高;进展定义为增加超过0.5。后囊下(PSC)白内障定义为混浊面积达1平方毫米或更大;进展定义为增加超过1平方毫米。

结果

在3040名符合参加随访检查条件的参与者中,2594人(占符合条件者的85%)参加了随访。随访时参与者的平均年龄为62.5岁,55%为女性。在5年期间至少摘除一枚晶状体的患者比例从基线时40至49岁人群中的0.5%增加到基线时80岁及以上人群中的35.7%。三种类型白内障的总体发病率如下:皮质性7.7%(95%置信区间[CL]=5.8 - 9.8),核性16.4%(95% CL = 12.1 - 20.8),PSC 7%(95% CL = 5.3 - 8.7)。白内障的总体进展情况为:皮质性14.3%(95% CL = 10.2 - 18.3),核性19.3%(95% CL = 15.9 - 22.7),PSC 20%(95% CL = 8.7 - 31.1)。发病率和进展率随年龄显著增加,但性别之间的比率无显著差异。

结论

这些白内障发病率数据证实了白内障在澳大利亚的公共卫生重要性。这些数据还支持制定初级预防计划和充足的手术服务以满足随着人口老龄化预期需求增加的必要性。

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