Lee John J, Moster Marlene R, Henderer Jeffrey D, Membreno Jaime H
Wills Eye Hospital Glaucoma Service, Philadelphia, Pennsylvania, USA.
Am J Ophthalmol. 2003 Jul;136(1):201-3. doi: 10.1016/s0002-9394(03)00150-8.
To evaluate pupil dilation from intracameral injection of nonpreserved 1% lidocaine.
Observational case series of 25 consecutive phakic trabeculectomies.
Patients were evaluated in the operating room setting and given one drop of topical tetracaine preoperatively. Nonpreserved 1% lidocaine (0.1 cc) was injected intracameraly into the anterior chamber through a paracentesis site at the corneal limbus. Pupil diameter was measured after instillation of topical tetracaine, before injection of intracameral lidocaine. Postinjection measurements were made at 1, 3, and 5 minutes.
The mean male pupil diameter was significantly greater than female dilation at every time point. The mean blue iris diameter was greater than brown at 1 and 3 minutes, but there was no difference at 5 minutes or more. There was no racial difference in the pupil dilation response to intracameral lidocaine.
Nonpreserved intracameral 1% lidocaine produces immediate pupil dilation in previously undilated phakic patients during trabeculectomy surgery.
评估前房内注射未保存的1%利多卡因后的瞳孔散大情况。
对连续25例有晶状体小梁切除术的观察性病例系列研究。
在手术室环境中对患者进行评估,术前给予一滴局部用丁卡因。通过角膜缘穿刺部位将0.1毫升未保存的1%利多卡因前房内注射到前房。在滴入局部用丁卡因后、前房内注射利多卡因前测量瞳孔直径。注射后在1、3和5分钟进行测量。
在每个时间点,男性瞳孔平均直径显著大于女性的散大程度。蓝色虹膜平均直径在1和3分钟时大于棕色虹膜,但在5分钟及以后无差异。前房内利多卡因引起的瞳孔散大反应不存在种族差异。
未保存的前房内1%利多卡因在小梁切除术期间可使术前未散瞳的有晶状体患者立即出现瞳孔散大。