治愈转移性癌症：来自睾丸生殖细胞肿瘤的经验教训。
Curing metastatic cancer: lessons from testicular germ-cell tumours.
作者信息
Masters John R W, Köberle Beate
机构信息
The Prostate Cancer Research Centre, Institute of Urology, University College London, 3rd Floor, 67 Riding House Street, London W1W 7EJ, UK.
出版信息
Nat Rev Cancer. 2003 Jul;3(7):517-25. doi: 10.1038/nrc1120.
DOI:10.1038/nrc1120
PMID:12835671
Abstract
Most metastatic cancers are fatal. More than 80% of patients with metastatic testicular germ-cell tumours (TGCTs), however, can be cured using cisplatin-based combination chemotherapy. Why are TGCTs more sensitive to chemotherapeutics than most other tumour types? Answers to this question could lead to new treatments for metastatic cancers.
摘要
大多数转移性癌症都是致命的。然而，超过80%的转移性睾丸生殖细胞肿瘤（TGCT）患者可以通过使用以顺铂为基础的联合化疗治愈。为什么TGCT比大多数其他肿瘤类型对化疗药物更敏感？这个问题的答案可能会带来转移性癌症的新疗法。
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