Luan X, Gross E
Department of Internal Medicine, Tongji Hospital, Tongji Medical University, Wuhan 430030.
J Tongji Med Univ. 2000;20(4):332-5. doi: 10.1007/BF02888196.
The inflammatory process associated with Crohn's disease often makes dissection difficult, even in open surgery. The aim of this study was to assess the technical feasibility, safety and indication of laparoscopic assisted procedures performed in patients with Crohn's disease. Records of patients undergoing surgical operation for Crohn's disease from 1993 to 1998 at our hospital were reviewed. Intestinal resection was performed laparoscopically in 24 patients (LAP) and by open technique in 23 patients(OPEN). No significant differences existed as to age, gender, body-mass-index and previous surgery. In the laparoscopic group, seven operations (CON) were converted to open laparotomy (29%) because of large inflammatory mass and/or fistula. The mean intraoperative blood loss was significantly higher in CON- and OPEN-groups than in LAP-group (P < 0.01). Major complications occurred only in one patient who underwent laparoscopic assisted high anterior resection. Patients who underwent laparoscopic operation tolerated p.o. liquids sooner than patients who underwent open surgery (median: 2 vs. 5 day, P < 0.05). Compared with the CON- and OPEN-groups, patients in LAP-group had lower analgesic requirements (median: 3 vs. 6 and 5 day, P < 0.01). The median postoperative length of stay was significantly shorter in LAP-group than in OPEN-group (median: 11 vs. 14 day, P < 0.05). Our study showed that LAP is technically feasible for Crohn's disease. The preoperative correct diagnosis and selection of indications are very important, because the laparoscopic mobilization and resection may be difficult or impossible in patients with large fixed masses, multiple complex fistulas, or recurrent Crohn's disease.
与克罗恩病相关的炎症过程常常使手术解剖变得困难,即便在开放手术中也是如此。本研究的目的是评估在克罗恩病患者中实施腹腔镜辅助手术的技术可行性、安全性及适应证。回顾了我院1993年至1998年因克罗恩病接受手术治疗患者的记录。24例患者接受了腹腔镜肠切除术(LAP组),23例患者接受了开放手术(OPEN组)。在年龄、性别、体重指数及既往手术史方面,两组间无显著差异。在腹腔镜组中,7例手术(CON组)因巨大炎性肿块和/或瘘管而中转开腹(29%)。CON组和OPEN组的术中平均失血量显著高于LAP组(P<0.01)。主要并发症仅发生在1例接受腹腔镜辅助高位前切除术的患者中。接受腹腔镜手术的患者比接受开放手术的患者更早耐受经口液体摄入(中位数:2天对5天,P<0.05)。与CON组和OPEN组相比,LAP组患者的镇痛需求更低(中位数:3天对6天和5天,P<0.01)。LAP组术后中位住院时间显著短于OPEN组(中位数:11天对14天,P<0.05)。我们的研究表明,腹腔镜辅助手术对于克罗恩病在技术上是可行的。术前正确诊断和适应证选择非常重要,因为对于有巨大固定肿块、多发复杂瘘管或复发性克罗恩病的患者,腹腔镜游离和切除可能困难甚至无法进行。