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克罗恩病的腹腔镜手术。适应证与结果。

Laparoscopic surgery in Crohn's disease. Indications and results.

作者信息

Reissman P, Salky B A, Edye M, Wexner S D

机构信息

Department of Colorectal Surgery, Cleveland Clinic Florida, 3000 W. Cypress Creek Road, Fort Lauderdale, FL 33309, USA.

出版信息

Surg Endosc. 1996 Dec;10(12):1201-3; discussion 1203-4. doi: 10.1007/s004649900279.

Abstract

BACKGROUND

An effort was made to assess the feasibility, safety, and outcome of laparoscopic procedures performed in patients with Crohn's disease.

METHODS

A prospectively maintained laparoscopic database was analyzed regarding operation time, intra- and postoperative complications, conversion to laparotomy, and length of hospitalization.Fifty-one patients (23 males and 28 females) with a mean age of 36 (20-79) years underwent a laparoscopic or laparoscopic-assisted procedure for Crohn's disease. The indications included terminal ileitis in 31 patients, colitis in 11, perianal disease in four, duodenal Crohn's disease in three, and rectovaginal and rectourethral fistula in one patient each. Thirty-two patients underwent an ileocolic resection; total abdominal colectomy with ileorectal anastomosis was performed in six patients with end ileostomy in one, take down of end ileostomy and ileorectal anastomosis in three, duodenal bypass gastrojejunostomy in three, and loop ileostomy in six patients.

RESULTS

The mean operating time was 2.4 (0.6-4.5) h and the mean length of hospital stay was 5.1 (3-18) days. Eight complications were noted in seven patients (14%), which included enterotomy in two patients, bleeding in two, stoma obstruction in two, pelvic sepsis in one, and efferent limb obstruction in one. The procedure was converted to laparotomy in seven patients (14%) due to a large inflammatory mass in five and to bleeding in two patients; there was no mortality.

CONCLUSION

Laparoscopic surgery is a feasible, versatile, and safe modality in the surgical management of Crohn's disease. Despite the often-malnourished state of these steroid-dependent patients with intraabdominal inflammatory conditions, morbidity, procedural length, and length-of-hospitalization data are all similar to results previously reported for less-challenging laparoscopic colorectal procedures.

摘要

背景

旨在评估对克罗恩病患者实施腹腔镜手术的可行性、安全性及手术结果。

方法

对一个前瞻性维护的腹腔镜数据库进行分析,内容包括手术时间、术中和术后并发症、中转开腹情况及住院时间。51例患者(23例男性,28例女性),平均年龄36岁(20 - 79岁),接受了针对克罗恩病的腹腔镜或腹腔镜辅助手术。手术指征包括:31例患者为末端回肠炎,11例为结肠炎,4例为肛周疾病,3例为十二指肠克罗恩病,1例患者同时存在直肠阴道瘘和直肠尿道瘘。32例患者接受了回结肠切除术;6例患者接受了全腹结肠切除加回直肠吻合术,其中1例患者行末端回肠造口术,3例患者行末端回肠造口回纳及回直肠吻合术,3例患者行十二指肠旁路胃空肠吻合术,6例患者行袢式回肠造口术。

结果

平均手术时间为2.4小时(0.6 - 4.5小时),平均住院时间为5.1天(3 - 18天)。7例患者(14%)出现8例并发症,其中2例患者发生肠切开,2例出血,2例造口梗阻,1例盆腔感染,1例输出袢梗阻。7例患者(14%)因5例存在巨大炎性包块及2例出血中转开腹;无死亡病例。

结论

腹腔镜手术在克罗恩病的外科治疗中是一种可行、多功能且安全的方式。尽管这些依赖类固醇的腹腔内炎症患者通常处于营养不良状态,但发病率、手术时长及住院时间数据均与先前报道的难度较小的腹腔镜结直肠手术结果相似。

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