Weise W, Bäcker U, Seidl S, Flacke H, Sondag D, Pirenne H, Schroeter E, Troonen H, Broeksma C, Heyermann H
Blood Transfusion Center, Munich, FRG.
Beitr Infusionsther. 1992;30:34-7.
An enzyme immunoassay for the detection of antibodies against structural and nonstructural domains of the hepatitis C virus (EIA-2) was compared to a first generation test (EIA-1) that can only detect antibodies against one nonstructural antigen (c100). EIA-2 revealed elevated detection rates as assessed in high risk and patient populations as well as lower repeat reactive rates in volunteer blood donors. Research test systems proved an increase in apparent specificity.
一种用于检测丙型肝炎病毒结构和非结构区域抗体的酶免疫测定法(EIA - 2)与第一代检测方法(EIA - 1)进行了比较,第一代检测方法只能检测针对一种非结构抗原(c100)的抗体。在高危人群和患者群体中评估发现,EIA - 2显示出更高的检测率,在无偿献血者中其重复反应率更低。研究测试系统证明其表观特异性有所提高。