Wray J, Radley-Smith R, Yacoub M
Cardiothoracic Unit, Harefield Hospital, Middlesex, UK.
Qual Life Res. 1992 Feb;1(1):41-6. doi: 10.1007/BF00435434.
Despite the increase in the use of heart and heart-lung transplantation as methods of treatment for children with end stage heart or lung disease, there is little documented research about the psychological implications of such procedures or about the effects of transplantation on quality of life. Twenty-eight children were studied before and 3 months after heart or heart-lung transplantation and compared with 28 normal children. Developmental and cognitive function were within the normal range, although performance was at a significantly lower level on a number of parameters compared with the normal group. There were no significant changes in any of the developmental or cognitive parameters after transplantation. Pre-operatively the prevalence of problem behaviour at home was significantly higher in the transplant group compared with the normal group, but there was a significant reduction in the prevalence of problem behaviour following transplantation. Early postoperative findings indicate an improvement in quality of life after heart or heart-lung transplantation but longer term follow-up is now necessary.
尽管心脏和心肺移植作为治疗终末期心脏病或肺病儿童的方法使用有所增加，但关于此类手术的心理影响或移植对生活质量的影响，几乎没有文献记载的研究。对28名儿童在心脏或心肺移植前及移植后3个月进行了研究，并与28名正常儿童进行了比较。发育和认知功能在正常范围内，尽管与正常组相比，在一些参数上表现明显较低。移植后任何发育或认知参数均无显著变化。术前，移植组在家中出现问题行为的患病率显著高于正常组，但移植后问题行为的患病率显著降低。术后早期结果表明，心脏或心肺移植后生活质量有所改善，但现在需要进行长期随访。
