病毒诊断中的重组抗原。
Recombinant antigens in viral diagnosis.
作者信息
Vornhagen R, Baur A, Jahn G, Hinderer W, Nebel-Schickel H, Horn J, Wolf H, Sonneborn H H
机构信息
Biotest AG, Research Department, Dreieichenhain, FRG.
出版信息
Beitr Infusionsther. 1992;30:78-81.
PMID:1284774
Abstract
DNA fragments coding for a variety of different viral antigens have been cloned and expressed in Escherichia coli. Selected purified recombinant antigens were used for detection of specific antibodies by means of the ELISA technique. This approach has been used for the development of four different ELISAs for the detection of HIV- and EBV-specific antibodies.
摘要
编码多种不同病毒抗原的DNA片段已被克隆并在大肠杆菌中表达。通过酶联免疫吸附测定（ELISA）技术，使用选定的纯化重组抗原来检测特异性抗体。这种方法已被用于开发四种不同的ELISA，用于检测HIV和EBV特异性抗体。
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