Tam C C, O'Brien S J, Adak G K, Meakins S M, Frost J A
Gastrointestinal Diseases Division, Public Health Laboratory Service, Communicable Disease Surveillance Centre, 61 Colindale Avenue, NW9 5EQ, London, UK.
J Infect. 2003 Jul;47(1):28-32. doi: 10.1016/s0163-4453(03)00042-2.
Campylobacters are the most common bacterial cause of infectious intestinal disease (IID) in temperate countries. C. jejuni is the predominant cause of campylobacter IID, but the impact of other, less prevalent species has largely been ignored. Here, we present estimates of the burden of indigenously acquired foodborne disease (IFD) due to Campylobacter coli, the second most common cause of human campylobacteriosis.
Data from surveillance sources and specific epidemiologic studies were used to calculate the number of illnesses, presentations to general practice (GP), hospital admissions, hospital occupancy and deaths due to indigenous foodborne C. coli IID in England and Wales for the year 2000.
We estimate that in the year 2000, C. coli accounted for over 25,000 cases of IFD. This organism was responsible for more than 12,000 presentations to GP, 1000 hospital admissions, nearly 4000 bed days of hospital occupancy and 11 deaths. The cost to patients and the National Health Service was estimated at nearly pound 4 million.
Although C. coli comprises a minority of human campylobacter disease, its health burden is considerable and greater than previously thought. Targeted research on this organism is required for its successful control.
弯曲杆菌是温带国家感染性肠道疾病（IID）最常见的细菌病因。空肠弯曲菌是弯曲杆菌性IID的主要病因，但其他不太常见的菌种的影响在很大程度上被忽视了。在此，我们给出了由结肠弯曲菌引起的本土食源性疾病（IFD）负担的估计值，结肠弯曲菌是人类弯曲菌病的第二大常见病因。
利用监测来源的数据和特定的流行病学研究，计算出2000年英格兰和威尔士因本土食源性结肠弯曲菌IID导致的疾病数量、全科医生（GP）诊疗次数、住院人数、住院天数和死亡人数。
我们估计，2000年结肠弯曲菌导致了超过25000例IFD病例。这种病菌导致了超过12000次全科医生诊疗、1000例住院、近4000个住院日以及11例死亡。对患者和国民医疗服务体系造成的成本估计接近400万英镑。
虽然结肠弯曲菌在人类弯曲菌病中占少数，但其对健康的负担相当大，且比之前认为的更严重。为成功控制这种病菌，需要对其进行针对性研究。
