Schumacher S
Urologische Klinik und Poliklinik der Rheinischen Friedrich-Wilhelms-Universität Bonn.
Urologe A. 2003 Jun;42(6):801-6. doi: 10.1007/s00120-003-0361-0. Epub 2003 Apr 26.
Overactive bladder (OAB) is generally not disease specific. Symptoms are frequency, nocturia, and urgency with or without urge incontinence. The prevalence of 16.6%, evaluated in six European countries, is surprisingly high. Causes for overactive bladder are an increase of sensory stimulation and/or a decrease of sensory threshold of the bladder or a disproportion between strength of afferent stimulation and central inhibition of micturition reflex resulting in detrusor overactivity. Overactive bladder is a symptom-based diagnosis. Urodynamics is an important diagnostic tool in daily routine. Urodynamics encompasses a spectrum of different techniques and is more than just cystometry. Simple cystometry or video cystometry should be carried out after evaluation with a frequency volume chart, flow rates, and residuals, mostly by ultrasound. Urodynamic observations should never be discussed separately but always together with history, symptoms, signs, and pathological findings. It is not necessary to perform a filling and voiding cystometry in each patient with symptoms and signs of overactive bladder. Indications for cystometry are prior to invasive therapy or where previous medical or surgical therapy has failed, after pelvic surgery or pelvic irradiation, in patients with signs or symptoms suggestive of an emptying disorder, in neurological disorders, or where there is any doubt about the diagnosis. Diagnostic evaluation of geriatric patients with overactive bladder can usually be accomplished with a basic assessment while invasive procedures should be the exception.
膀胱过度活动症(OAB)通常并非特定疾病。症状包括尿频、夜尿症以及尿急,伴有或不伴有急迫性尿失禁。在六个欧洲国家进行评估,其患病率为16.6%,这一数字高得出奇。膀胱过度活动症的病因是感觉刺激增加和/或膀胱感觉阈值降低,或者传入刺激强度与排尿反射中枢抑制之间失衡,导致逼尿肌过度活动。膀胱过度活动症是基于症状的诊断。尿动力学检查是日常临床中的重要诊断工具。尿动力学检查包含一系列不同技术,不仅仅是膀胱测压。简单膀胱测压或影像膀胱测压应在通过频率-容量图、尿流率和残余尿量评估后进行,大多采用超声检查。尿动力学检查结果绝不应单独讨论,而应始终结合病史、症状、体征和病理检查结果进行分析。并非每个有膀胱过度活动症症状和体征的患者都必须进行充盈和排尿膀胱测压。膀胱测压的适应证包括在进行侵入性治疗之前,或既往药物或手术治疗失败后,盆腔手术后或盆腔放疗后,有提示排空障碍的体征或症状的患者,患有神经系统疾病的患者,或对诊断存在任何疑问的情况。老年膀胱过度活动症患者的诊断评估通常通过基本评估即可完成,侵入性检查应为例外情况。