Haruyama Miho, Yuzawa Mitsuko
Department of Ophthalmology, Surugadai Hospital, Nihon University, 1-8-13 Surugadai, Kanda, Chiyoda-ku, Tokyo 101-8309, Japan.
Nippon Ganka Gakkai Zasshi. 2003 Jun;107(6):311-5.
We evaluate the utility of laser photocoagulation of extrafoveal choroidal neovascularization (CNV) in angioid streaks.
Eleven eyes of 10 patients with extrafoveal CNV secondary to angioid streaks that underwent direct laser photocoagulation were followed for 5 months or more. We performed an intense laser photocoagulation of a CNV area determined by fluorescein angiography. We evaluated CNV diameter, the shortest distance between CNV and the fovea, the best visual acuity, the final visual acuity, existence, period, and region of the recurrence, and changes in fundus findings.
The logarithm of the minimum angle of resolution (log MAR) final visual acuity in 9 eyes deteriorated more than two levels. The recurrence of CNV was observed in 11 eyes, in 9 eyes CNV expanded and involved the fovea, and in two eyes photocoagulation was performed but caused an atrophic creep and resulted in scar formation including the fovea.
Based on these results, laser photocoagulation is not a good therapy for CNV in angioid streaks.
我们评估激光光凝治疗血管样条纹中黄斑中心凹外脉络膜新生血管（CNV）的效用。
对10例因血管样条纹继发黄斑中心凹外CNV而接受直接激光光凝治疗的患者的11只眼进行了5个月或更长时间的随访。我们对荧光素血管造影确定的CNV区域进行了强化激光光凝。我们评估了CNV直径、CNV与黄斑中心凹之间的最短距离、最佳视力、最终视力、复发的存在情况、时期和区域，以及眼底表现的变化。
9只眼的最小分辨角对数（log MAR）最终视力恶化超过两级。11只眼中观察到CNV复发，9只眼中CNV扩大并累及黄斑中心凹，2只眼进行了光凝但导致萎缩性蔓延并形成包括黄斑中心凹在内的瘢痕。
基于这些结果，激光光凝不是治疗血管样条纹中CNV的良好疗法。
