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毛细管电泳中的电容耦合非接触式电导检测

Capacitively coupled contactless conductivity detection in capillary electrophoresis.

作者信息

Zemann Andreas J

机构信息

Institute of Analytical Chemistry and Radiochemistry, Leopold-Franzens-University of Innsbruck, Innsbruck, Austria.

出版信息

Electrophoresis. 2003 Jun;24(12-13):2125-2137. doi: 10.1002/elps.200305476.

DOI:10.1002/elps.200305476
PMID:12858385
Abstract

Capacitively coupled contactless conductivity detection (C(4)D) has become an accepted detection method in capillary electrophoresis (CE) for a variety of analytes. Advantages of this technique over optical detection modes and galvanic contact conductivity detection include great flexibility in capillary handling and rather simple mechanical parts and electronics, as it can be performed in an on-capillary mode. Furthermore, the detection principle can be used with capillaries made of other materials than fused silica (PEEK, Teflon), with chip-based separation technologies, or with capillaries having very small inner diameters. This review presents a discussion of the published literature on C(4)D for CE and capillary electrochromatography.

摘要

电容耦合非接触式电导检测(C(4)D)已成为毛细管电泳(CE)中用于多种分析物的一种公认的检测方法。与光学检测模式和电流接触式电导检测相比,该技术的优势包括毛细管操作具有很大的灵活性,以及机械部件和电子设备相当简单,因为它可以在毛细管上进行操作。此外,该检测原理可用于除熔融石英之外的其他材料制成的毛细管(聚醚醚酮、聚四氟乙烯)、基于芯片的分离技术或内径非常小的毛细管。本综述讨论了已发表的关于用于CE和毛细管电色谱的C(4)D的文献。

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