Derk Chris T, Jimenez Sergio A
Division of Rheumatology, Department of Medicine, Thomas Jefferson University, Philadelphia, Pennsylvania 19107-5541, USA.
J Rheumatol. 2003 Jul;30(7):1616-20.
We report a case of Goodpasture-like syndrome developing in a patient who was treated with D-penicillamine for the diffuse form of systemic sclerosis. This unusual pulmonary-renal syndrome has been described on rare occasions in patients receiving D-penicillamine. This complication appeared to be uniformly fatal unless treated with aggressive immunotherapy. We review the cases reported to date in the literature and describe the clinical characteristics, therapy, and outcome of this group of patients.
我们报告了1例在接受青霉胺治疗弥漫性系统性硬化症的患者中发生的类Goodpasture综合征病例。这种不寻常的肺-肾综合征在接受青霉胺治疗的患者中鲜有报道。除非采用积极的免疫治疗，否则这种并发症似乎无一例外是致命的。我们回顾了文献中迄今为止报道的病例，并描述了这组患者的临床特征、治疗方法及转归。
