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通过比利时哨点网络进行的卒中登记及影响卒中死亡率的因素。

Registration of stroke through the Belgian sentinel network and factors influencing stroke mortality.

作者信息

Devroey Dirk, Van Casteren Viviane, Buntinx Frank

机构信息

Scientific Institute Public Health, Brussels, Belgium.

出版信息

Cerebrovasc Dis. 2003;16(3):272-9. doi: 10.1159/000071127.

DOI:10.1159/000071127
PMID:12865616
Abstract

INTRODUCTION

Stroke is one of the leading causes of death. Belgian stroke mortality rates are only available from the death certificates notification.

OBJECTIVES

To estimate stroke incidence, mortality and case fatality, to compare our figures with those available from the death certificates notification and from neighboring countries, and identifying factors influencing survival.

METHODS

A nationwide prospective registration by 178 Belgian general practitioners recording all cerebrovascular events in 1998-1999. All events, including those for which medical care was immediately found in hospital, were included.

RESULTS

The yearly age-and-gender-adjusted stroke attack rates were estimated at 185 cases per 100,000 inhabitants (95% CI = 169-202). After 12 months, 47% of the patients died, resulting in an estimated yearly stroke mortality rate of 88 per 100,000 inhabitants (95% CI = 73-105). The case fatality rate among men (39%; 95% CI = 29-51) was lower than among women (50%; 95% CI = 39-63) (p < 0.05). In a forward stepwise logistic regression diabetes, stroke history, hemorrhagic stroke, coma, swallow deficit and urinary incontinence had a negative influence on stroke survival. Treated hypertension had a beneficial effect on survival.

CONCLUSIONS

Stroke mortality rates estimated by the sentinel practices are fairly comparable with those based on the death certificates notification. The stroke attack rates correspond with those of neighboring countries. The role of treated hypertension on the outcome of strokes remains controversial in this registration.

摘要

引言

中风是主要死因之一。比利时的中风死亡率仅可从死亡证明通知中获取。

目的

估计中风发病率、死亡率和病死率,将我们的数据与死亡证明通知及邻国的数据进行比较,并确定影响生存的因素。

方法

由178名比利时全科医生进行全国性前瞻性登记,记录1998 - 1999年所有脑血管事件。所有事件,包括那些在医院立即得到医疗救治的事件,均被纳入。

结果

年龄和性别调整后的年中风发病率估计为每10万居民185例(95%置信区间 = 169 - 202)。12个月后,47%的患者死亡,导致估计的年中风死亡率为每10万居民88例(95%置信区间 = 73 - 105)。男性的病死率(39%;95%置信区间 = 29 - 51)低于女性(50%;95%置信区间 = 39 - 63)(p < 0.05)。在向前逐步逻辑回归分析中,糖尿病、中风病史、出血性中风、昏迷、吞咽障碍和尿失禁对中风生存有负面影响。治疗高血压对生存有有益影响。

结论

哨兵实践估计的中风死亡率与基于死亡证明通知的死亡率相当。中风发病率与邻国的发病率相符。在本次登记中,治疗高血压对中风结局的作用仍存在争议。

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