Homko Carol J, Reece E Albert
General Clinical Research Center, Temple University School of Medicine, 3401 N. Broad Street, 4 West, Philadelphia, PA 19140, USA.
Curr Diab Rep. 2003 Aug;3(4):313-8. doi: 10.1007/s11892-003-0023-z.
The prevalence of type 2 diabetes mellitus is increasing in children and adolescents worldwide, particularly among minority youth. This has led to an increase in the number of pregnancies complicated by type 2 diabetes, which has now exceeded pregnancies complicated by type 1 diabetes. Although the data are somewhat limited, those studies that are available seem to indicate that the rate of adverse maternal and fetal outcomes is at least as great, if not greater, for type 2 as for type 1 diabetes. It has been postulated that some of the excess risk is due to the fact that women with type 2 diabetes are older, heavier, less likely to seek early prenatal care, and are generally in less satisfactory glycemic control. This article reviews the existing data on pregnancies complicated by type 2 diabetes and the implications for management and prevention.
全球儿童和青少年2型糖尿病的患病率正在上升，尤其是在少数族裔青少年中。这导致了2型糖尿病合并妊娠的数量增加，目前已超过1型糖尿病合并妊娠的数量。尽管数据有限，但现有研究似乎表明，2型糖尿病孕产妇和胎儿不良结局的发生率至少与1型糖尿病一样高，甚至可能更高。据推测，部分额外风险是由于2型糖尿病女性年龄较大、体重较重、不太可能寻求早期产前护理，且血糖控制总体不太理想。本文综述了关于2型糖尿病合并妊娠的现有数据及其对管理和预防的影响。
