Bergonse Fabiane N, Rabello Suzy M, Barreto Rodrigo L, Romiti Ricardo, Nico Marcello Menta S, Aoki Valéria, Reis Vitor Manoel S, Rivitti Evandro A
Hospital das Clínicas, University of São Paulo, São Paulo, Brazil.
Pediatr Dermatol. 2003 Jul-Aug;20(4):323-6. doi: 10.1046/j.1525-1470.2003.20410.x.
Olmsted syndrome is a rare variety of transgredient palmoplantar keratoderma with an undefined inheritance pattern. It starts in the neonatal period or in childhood and has a progressive and extremely disabling course. We report two new, unrelated patients with Olmsted syndrome, one with the early signs and symptoms of the disorder, the other showing the full-blown spectrum of the syndrome during a 30-year follow-up period.