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伴有口腔受累的奥姆斯特德综合征,包括牙齿过早脱落。

Olmsted syndrome with oral involvement, including premature teeth loss.

作者信息

Alotaibi Ahmed K, Alotaibi Mazen K, Alsaeed Suliman, Alyahya Ahmad, Shuler Charles F

机构信息

Bachelor of Dental Surgery Collage of Dentistry, King Saud University, Riyadh, Saudi Arabia.

出版信息

Odontology. 2015 May;103(2):241-5. doi: 10.1007/s10266-014-0148-3. Epub 2014 Jan 29.

DOI:10.1007/s10266-014-0148-3
PMID:24474548
Abstract

INTRODUCTION

Olmsted syndrome is a rare palmoplantar keratodermal disease that has not previously been reported to have an association with periodontal disease. The aim of this study is to report and document a case of Olmsted syndrome with evidence of severe periodontal disease.

CASE REPORT

A 38-year old Saudi male patient presented to the dental clinic diagnosed previously with Olmsted syndrome. Clinical and radiographic examinations were done and provided evidence of the typical clinical findings in Olmsted syndrome and evidence of severe periodontal disease. The patient had severe generalized hyperkeratotic lesions on the palms, soles, and perioral skin as well as hyperkeratosis of oral mucosa at multiple sites.

CONCLUSION

This case report documents the first reported case of Olmsted syndrome to be associated with severe periodontal disease. The altered differentiation of oral mucosa linked to Olmsted syndrome may contribute to the periodontal disease. Patients diagnosed with this syndrome should receive a comprehensive oral examination to determine whether periodontal destruction is a significant component of their disease or not.

摘要

引言

奥姆斯特德综合征是一种罕见的掌跖角化皮肤病,此前尚无与牙周病相关的报道。本研究的目的是报告并记录一例伴有严重牙周病证据的奥姆斯特德综合征病例。

病例报告

一名38岁的沙特男性患者前往牙科诊所就诊,此前被诊断为奥姆斯特德综合征。进行了临床和影像学检查,结果显示有奥姆斯特德综合征的典型临床特征以及严重牙周病的证据。该患者手掌、脚底和口周皮肤有严重的广泛性角化过度病变,口腔黏膜多处也有角化过度。

结论

本病例报告记录了首例与严重牙周病相关的奥姆斯特德综合征病例。与奥姆斯特德综合征相关的口腔黏膜分化改变可能导致牙周病。被诊断为此综合征的患者应接受全面的口腔检查,以确定牙周破坏是否是其疾病的重要组成部分。

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