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[需氧芽孢杆菌的细胞外氨基酸]

[Extracellular amino acids of aerobic spore-forming bacteria].

作者信息

Smirnov V V, Reznik S R, Kudriavtsev V A, Osadchaia A I, Safronova L A

出版信息

Mikrobiologiia. 1992 Sep-Oct;61(5):865-72.

PMID:1287408
Abstract

An ability to synthesize and accumulate in the growth medium for extracellular amino acids of 108 strains of 13 aerobic sporeforming bacteria species at deep cultivation on the simple synthetic glucose-mineral liquid nutrient medium optimized for the representatives of this genus. Has been studied the bacillus strains studied in the present conditions synthesize 19 amino acids and 2 amino carbons in different quantities and combinations. Amino acids being synthesized the most and least by these microorganisms have been determined in quantitative expression. Extracellular amino acid accumulation was proved to be a strain property not of genus. In general, the genus studied was evaluated as active one in amino acid production. The most active strains may present an interest as initials for further selective obtaining of producers of separate amino acids. The outlook for aerobic bacilli strains having marked amino-synthesizing properties and complex of other biological activities is being discussed for construction of medicinal and prophylactic of live microbial culture preparations.

摘要

在针对该属代表优化的简单合成葡萄糖 - 矿物质液体营养培养基上进行深层培养时,对13种需氧芽孢杆菌的108株菌株在生长培养基中合成并积累细胞外氨基酸的能力进行了研究。研究的芽孢杆菌菌株在当前条件下合成19种氨基酸和2种氨基碳,其数量和组合各不相同。已通过定量表达确定了这些微生物合成最多和最少的氨基酸。细胞外氨基酸积累被证明是菌株特性而非属的特性。总体而言,所研究的属在氨基酸生产方面被评估为活跃的属。最活跃的菌株可能作为进一步选择性获得单独氨基酸生产者的起始菌株而受到关注。正在讨论具有显著氨基酸合成特性和其他生物活性复合体的需氧芽孢杆菌菌株在构建药用和预防性活微生物培养制剂方面的前景。

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