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对间日疟原虫感染人类期间贫血情况的回顾性研究。

A retrospective examination of anemia during infection of humans with Plasmodium vivax.

作者信息

Collins William E, Jeffery Geoffrey M, Roberts Jacquelin M

机构信息

Division of Parasitic Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30341, USA.

出版信息

Am J Trop Med Hyg. 2003 Apr;68(4):410-2.

PMID:12875288
Abstract

A retrospective examination was made of archival data on 98 patient episodes of infection with Plasmodium vivax occurring over a period of 4-11 weeks to document changes in hemoglobin (Hb) concentrations associated with continuing parasitemia. The mean percentage change in the Hb concentration for each of the 10 seven-day intervals was -13.4, -10.9, -4.8, 0.12, 0.94, 4.0, 0.69, 11.6, 2.4, and 8.3, respectively. An equilibrium appeared to be established between weeks 4 and 6. Decreases in Hb concentrations were greatest following the first week of parasitemia. Total restoration to preinfection levels did not occur during persistent parasitemia.

摘要

对98例间日疟原虫感染患者病程长达4 - 11周的档案数据进行回顾性检查,以记录与持续寄生虫血症相关的血红蛋白(Hb)浓度变化。在10个为期7天的时间段内,Hb浓度的平均百分比变化分别为-13.4、-10.9、-4.8、0.12、0.94、4.0、0.69、11.6、2.4和8.3。在第4周和第6周之间似乎建立了平衡。寄生虫血症第一周后Hb浓度下降最为明显。在持续寄生虫血症期间,Hb浓度并未完全恢复到感染前水平。

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