Feltbower R G, McKinney P A, Campbell F M, Stephenson C R, Bodansky H J
University of Leeds, UK.
Arch Dis Child. 2003 Aug;88(8):676-9. doi: 10.1136/adc.88.8.676.
Following recent reports of increased numbers of adolescents being diagnosed with the adult or type 2 form of diabetes we aimed to describe the prevalence of both type 2 and other forms of diabetes in an urban population of children and young people in northern England.
A hospital based cross sectional study was performed in patients aged < or =30 years attending diabetic clinics in Leeds during the year 2000.
A total of 677 subjects were identified, of whom 621 (92%) and 37 (5%) had type 1 and type 2 diabetes respectively. Four patients had confirmed maturity onset diabetes of the young, while the cause was uncertain for four. Median age of all patients was 22 years, with 396 (58%) aged 20-30; 32/37 patients with type 2 diabetes were aged 20-30. The prevalence of type 2 diabetes was 0.13 per 1000 overall, compared to 2.2 per 1000 for patients with type 1 diabetes. Of all type 2 diabetes patients, 24% were south Asian compared to 5% of the background population; 87% were categorised into the two least affluent tertiles of the Townsend score. This link with deprivation was not explained by the proportion of Asian patients across tertiles (approximately 25%).
This study shows extremely low prevalence of type 2 diabetes in 10-19 year olds, but will provide a baseline for future comparisons. Overall, type 2 diabetes is seen more commonly in south Asians, and an association with deprivation is suggested.
近期有报道称,被诊断为成人型或2型糖尿病的青少年人数有所增加。我们旨在描述英格兰北部城市儿童和青少年人群中2型糖尿病及其他糖尿病类型的患病率。
2000年,在利兹糖尿病诊所对年龄小于或等于30岁的患者进行了一项基于医院的横断面研究。
共识别出677名受试者,其中621人(92%)患有1型糖尿病,37人(5%)患有2型糖尿病。4名患者确诊为青年成熟期糖尿病,另有4名患者病因不明。所有患者的中位年龄为22岁,其中396人(58%)年龄在20至30岁之间;37名2型糖尿病患者中有32人年龄在20至30岁之间。2型糖尿病的总体患病率为每1000人中有0.13例,而1型糖尿病患者的患病率为每1000人中有2.2例。在所有2型糖尿病患者中,24%为南亚裔,而背景人群中这一比例为5%;87%的患者被归类为汤森得分最低的两个贫困三分位数。这种与贫困的关联无法用各三分位数中亚洲患者的比例(约25%)来解释。
本研究显示10至19岁青少年中2型糖尿病的患病率极低,但将为未来的比较提供一个基线。总体而言,2型糖尿病在南亚裔中更为常见,且提示与贫困有关联。