Forouhi N G, Merrick D, Goyder E, Ferguson B A, Abbas J, Lachowycz K, Wild S H
Yorkshire and Humber Public Health Observatory, Alcuin Research and Resource Centre, The University of York, York, UK.
Diabet Med. 2006 Feb;23(2):189-97. doi: 10.1111/j.1464-5491.2005.01787.x.
To estimate the total prevalence of diabetes mellitus (diagnosed and undiagnosed) at national, regional and local level in England to support health-care planning and delivery.
An epidemiological model was constructed by applying age-sex-ethnic-specific reference prevalence rates from epidemiological studies to resident populations (2001 census) of England at national, regional, and local authority/Primary Care Trust levels.
Estimated prevalence of total diabetes for all persons in England was 4.41% in 2001, equating to 2 168 000 persons. Type 2 diabetes was estimated to affect 2 002 000 persons (92.3%) and Type 1 diabetes 166 000 persons (7.7%). Diabetes prevalence was estimated to be higher in women (5.17%) than men (3.61%). People from ethnic minority groups had higher crude prevalence than White Europeans (4.29, 5.69, 6.63 and 2.13% among White Europeans, Black African/Caribbeans, South Asians and 'other' groups, respectively). Prevalence increased sharply with age (0.33, 3.37 and 13.92%, respectively, in those aged 0-29, 30-59 and 60+ years). The model allows use of user-defined population denominator estimates to derive numbers and prevalence of people with diabetes for a given local population group, such as at ward or general practice level.
Self-reported diabetes prevalence estimates from community surveys underestimate the true burden of diabetes. The model can be used to derive the expected total prevalence of diabetes in health areas that lack reliable data to facilitate the implementation of the National Service Framework for diabetes. It will also allow estimates of future diabetes prevalence to be derived, and can potentially be used for prevalence estimates in all of the UK.
评估英格兰全国、地区及地方层面糖尿病(包括已诊断和未诊断病例)的总体患病率,以支持医疗保健规划与服务提供。
通过将流行病学研究中按年龄、性别、种族划分的参考患病率应用于英格兰全国、地区及地方当局/初级保健信托层面的常住人口(2001年人口普查数据),构建了一个流行病学模型。
2001年,英格兰所有人的糖尿病总体患病率估计为4.41%,即216.8万人。估计2型糖尿病患者有200.2万人(92.3%),1型糖尿病患者有16.6万人(7.7%)。糖尿病患病率估计女性(5.17%)高于男性(3.61%)。少数族裔人群的粗患病率高于欧洲白人(欧洲白人、非洲/加勒比黑人、南亚人和“其他”群体的患病率分别为4.29%、5.69%、6.63%和2.13%)。患病率随年龄急剧上升(0 - 29岁、30 - 59岁和60岁及以上人群的患病率分别为0.33%、3.37%和13.92%)。该模型允许使用用户定义的人口分母估计值,以得出给定当地人群(如病房或全科医疗层面)的糖尿病患者数量和患病率。
社区调查中自我报告的糖尿病患病率估计值低估了糖尿病的实际负担。该模型可用于在缺乏可靠数据的健康区域得出糖尿病的预期总体患病率,以促进糖尿病国家服务框架的实施。它还能用于推导未来糖尿病患病率的估计值,并有可能用于整个英国的患病率估计。