Gatling W, Budd S, Walters D, Mullee M A, Goddard J R, Hill R D
Department of Diabetes, Poole Hospital, Dorset, UK.
Diabet Med. 1998 Dec;15(12):1015-21. doi: 10.1002/(SICI)1096-9136(1998120)15:12<1015::AID-DIA719>3.0.CO;2-K.
This study examined the prevalence of diagnosed diabetes mellitus in a defined population over 13 years by undertaking cross-sectional surveys on 3 occasions between 1983 and 1996. The study population consisted of all the people registered with 10 general (primary care) practices at the time of each survey; 90660 in 1983/4; 97122 in 1988/9; and 86287 in 1996. Ascertainment of cases was by a surveillance programme in general practice and the hospital diabetes department. The number of diabetic patients increased significantly over the study period: in 1983/4, there were 917 patients, crude prevalence 1.01% (95% CI 0.95-1.08%); in 1988/9, 1150 patients, crude prevalence 1.17% (1.12-1.25%); and in 1996, 1604 patients, crude prevalence 1.86% (1.77-1.95%). The prevalence adjusted to the age and sex distribution of the UK was 0.97% (95% CI 0.90-1.03%) in 1983/4, 1.05% (0.99-1.11%) in 1988/9 and 1.55% (1.48-1.63%) in 1996. The main increase in prevalence was due to Type 2 diabetes mellitus, crude prevalence 0.75% (95% CI 0.69-0.81%) in 1983/4, 0.92% (0.86-0.98%) in 1988/9 and 1.52% (1.44-1.60%) in 1996 rather than Type 1 diabetes mellitus, crude prevalence 0.25% (0.21-0.28%) in 1983/4, 0.25% (0.22-0.28%) in 1988/9 and 0.34% (0.30-0.38%) in 1996. During the study period, the crude prevalence of diagnosed diabetes was significantly greater in men than women; in 1983/4 men 1.1% (95% CI 1.00-1.20%) versus women 0.93% (0.84-1.02%); in 1988/9, men 1.31% (1.21-1.41%) versus women 1.07% (0.98-1.16%); and in 1996, men 2.13% (2.00-2.27%) versus women 1.60% (1.49-1.72%). This difference was statistically significant in the 1988/9 and 1996 surveys. In conclusion, over 13 years there was a significant increase of 83.6% in the prevalence of diagnosed diabetes mellitus in the Poole area, with the UK age and sex adjusted prevalence increasing by 60.7%.
本研究通过在1983年至1996年间进行3次横断面调查，对特定人群中确诊糖尿病的患病率进行了为期13年的研究。研究人群包括每次调查时在10家全科（初级保健）诊所登记的所有人；1983/4年度为90660人；1988/9年度为97122人；1996年度为86287人。病例的确定通过全科医疗和医院糖尿病科的监测项目进行。在研究期间，糖尿病患者数量显著增加：1983/4年度有917名患者，粗患病率为1.01%（95%可信区间0.95 - 1.08%）；1988/9年度有1150名患者，粗患病率为1.17%（1.12 - 1.25%）；1996年度有1604名患者，粗患病率为1.86%（1.77 - 1.95%）。根据英国年龄和性别分布调整后的患病率在1983/4年度为0.97%（95%可信区间0.90 - 1.03%），1988/9年度为1.05%（0.99 - 1.11%），1996年度为1.55%（1.48 - 1.63%）。患病率的主要增加归因于2型糖尿病，1983/4年度粗患病率为0.75%（95%可信区间0.69 - 0.81%），1988/9年度为0.92%（0.86 - 0.98%），1996年度为1.52%（1.44 - 1.60%），而非1型糖尿病，1983/4年度粗患病率为0.25%（0.21 - 0.28%），1988/9年度为0.25%（0.22 - 0.28%），1996年度为0.34%（0.30 - 0.38%）。在研究期间，确诊糖尿病的粗患病率男性显著高于女性；1983/4年度男性为1.1%（95%可信区间1.00 - 1.20%），女性为0.93%（0.84 - 1.02%）；1988/9年度，男性为1.31%（1.21 - 1.41%），女性为1.07%（0.98 - 1.16%）；1996年度，男性为2.13%（2.00 - 2.27%），女性为1.60%（1.49 - 1.72%）。这种差异在1988/9和1996年的调查中具有统计学意义。总之，在13年中，普尔地区确诊糖尿病的患病率显著增加了83.6%，根据英国年龄和性别调整后的患病率增加了60.7%。
