Nouraei S M, Wallis J P, Bolton D, Hasan A
Regional Cardiothoracic Centre, Freeman Hospital, Newcastle upon Tyne NE7 7DN, UK.
Br J Anaesth. 2003 Aug;91(2):292-4. doi: 10.1093/bja/aeg143.
We report a case of successful management of transfusion-related acute lung injury (TRALI) with prolonged cardiopulmonary bypass support in a 4-yr-old patient undergoing elective cardiac surgery. TRALI was diagnosed clinically and immunologically by detection of reactive antibodies in a unit of fresh frozen plasma that had been administered to the patient. The aetiology and management of TRALI are briefly discussed and possible implications of this case for the management of TRALI are highlighted.
我们报告了一例在接受择期心脏手术的4岁患者中，通过延长体外循环支持成功治疗输血相关急性肺损伤（TRALI）的病例。通过检测输注给该患者的一袋新鲜冰冻血浆中的反应性抗体，临床和免疫方面诊断为TRALI。本文简要讨论了TRALI的病因及治疗，并强调了该病例对TRALI治疗的潜在意义。
