Nossaman Bobby D
Department of Anesthesiology, Ochsner Clinic Foundation, New Orleans, LA.
Ochsner J. 2008 Spring;8(1):32-8.
Transfusion of allogeneic blood products is given for correction of coagulation deficits and for the improvement in oxygen-carrying capacity or delivery. Blood transfusion has become safer following the advancement in blood testing using state-of-the-art viral assays; however, there continues to exist a variety of noninfectious transfusion risks that still remain and that cannot be entirely eliminated. Research is now directed towards understanding these lesser-known, but serious transfusion-related complications. This purpose of this review is to discuss a serious noninfectious cause of acute lung injury, transfusion-related acute lung injury (TRALI), which occurred in 2 recent cases in the intensive care unit, and to review the current literature of this syndrome.
输注异体血液制品用于纠正凝血缺陷以及提高氧携带能力或氧输送。随着采用先进病毒检测方法的血液检测技术取得进展，输血已变得更加安全；然而，仍然存在多种非感染性输血风险，这些风险依然存在且无法完全消除。目前的研究方向是了解这些鲜为人知但严重的输血相关并发症。本综述的目的是讨论急性肺损伤的一种严重非感染性病因——输血相关急性肺损伤（TRALI），该病症在重症监护病房最近发生的2例病例中出现，并回顾该综合征的当前文献。
