Akkuş Selami, Senol Altug, Ayvacioglu Naime Bayram, Tunc Ercan, Eren Ibrahim, Isler Mehmet
Department of Physical Medicine and Rehabilitation, Suleyman Demirel University Medical School, Isparta, Turkey.
Rheumatol Int. 2004 Mar;24(2):106-9. doi: 10.1007/s00296-003-0328-x. Epub 2003 Jul 16.
Irritable bowel syndrome (IBS) and fibromyalgia (FM) are common functional diseases in adult women. The aim of this study was to investigate whether female predominance in IBS is related to FM. Fifty patients with IBS and 50 healthy controls were enrolled. All participants answered questionnaires including personal and medical history. In addition, psychiatric interviews were conducted. Patients were divided into two groups according to the coexistence of FM ( IBS+FM or IBS only). The data obtained from patients with or without FM and the control group were compared. There was a significant female predominance in patients with IBS+FM (83.4%, F:M=5:1), but IBS-only patients consisted mainly of males (59.4%, F:M=2:3) ( P<0.01). Comparison of IBS+FM and IBS-only patients showed no significant difference in depression and anxiety status. However, both anxiety and depression scores were found to be higher in female IBS patients than their male counterparts ( P<0.01 and P<0.05, respectively). Our findings suggest that the female predominance in IBS patients may result from coexisting FM.
肠易激综合征（IBS）和纤维肌痛（FM）是成年女性常见的功能性疾病。本研究的目的是调查IBS中女性占主导地位是否与FM有关。招募了50例IBS患者和50名健康对照者。所有参与者都回答了包括个人和病史的问卷。此外，还进行了精神科访谈。患者根据FM的共存情况分为两组（IBS+FM或仅IBS）。比较了有或没有FM的患者以及对照组获得的数据。IBS+FM患者中女性占显著优势（83.4%，女性：男性=5：1），但仅IBS患者主要为男性（59.4%，女性：男性=2：3）（P<0.01）。IBS+FM患者与仅IBS患者的比较显示，抑郁和焦虑状态无显著差异。然而，发现女性IBS患者的焦虑和抑郁评分均高于男性患者（分别为P<0.01和P<0.05）。我们的研究结果表明，IBS患者中女性占主导地位可能是由共存的FM导致的。
