Makarieva Tatyana N, Rho Jung-Rae, Lee Hyi-Seung, Santalova Elena A, Stonik Valentin, Shin Jongheon
Marine Natural Products Chemistry Laboratory, Pacific Institute of Bioorganic Chemistry, Far-Eastern Branch of Russian Academy of Sciences, Vladivostok 690022, Russia.
J Nat Prod. 2003 Jul;66(7):1010-2. doi: 10.1021/np030141p.
Three new sesterterpene sulfates, halisulfates 8-10 (1-3), were isolated from the Australian sponge Darwinella australensis. The structures of these compounds were determined by combined spectroscopic methods. The stereochemistry of the decalin moiety was assigned on the basis of NMR interpretations. Halisulfates 9 and 10 inhibited cell division of sea urchin eggs in moderate concentration.
从澳大利亚海绵达尔文氏海绵(Darwinella australensis)中分离出三种新的倍半萜硫酸酯,即卤硫酸酯8 - 10(1 - 3)。通过综合光谱方法确定了这些化合物的结构。根据核磁共振(NMR)解释确定了十氢化萘部分的立体化学。卤硫酸酯9和10在中等浓度下抑制海胆卵的细胞分裂。