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体育中的合成代谢类固醇:生物化学、临床及分析视角

Anabolic steroids in sport: biochemical, clinical and analytical perspectives.

作者信息

Kicman Andrew T, Gower D B

机构信息

Address Drug Control Centre, King's College London, London SE1 9NN, UK.

出版信息

Ann Clin Biochem. 2003 Jul;40(Pt 4):321-56. doi: 10.1258/000456303766476977.

DOI:10.1258/000456303766476977
PMID:12880534
Abstract

International Olympic Committee accredited laboratories play a key role in upholding the principle of fair play and innate ability, as desired by the majority of sports competitors and spectators. Not only does doping damage the image of sport, but it can also be harmful to the individual. The great majority of samples test negative but, when an adverse finding is declared, the analytical data must be of a sufficiently high standard to withstand legal challenges by third parties. The most widely misused performance-enhancing drugs are the anabolic-androgenic steroids, commonly referred to as 'anabolic steroids'. This review attempts to address the complex issues concerning anabolic steroids in sport by considering the clinical, biochemical and analytical perspectives.

摘要

国际奥委会认可的实验室在维护公平竞赛原则和运动员天赋能力方面发挥着关键作用,这也是大多数体育参赛者和观众所期望的。使用兴奋剂不仅会损害体育运动的形象,还可能对个人有害。绝大多数样本检测结果为阴性,但当宣布出现不利检测结果时,分析数据必须达到足够高的标准,以经受第三方的法律质疑。滥用最为广泛的增强运动表现药物是合成代谢雄性类固醇,通常被称为“合成代谢类固醇”。本综述试图通过从临床、生化和分析等角度来探讨体育运动中与合成代谢类固醇有关的复杂问题。

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