Solov'ev A S
Biull Eksp Biol Med. 1992 Oct;114(10):382-3.
The study was made of spleen cells proliferative response to mitogens PHA, Con A or alloantigens in relation to hyperthermia effects. Acute hyperthermia (rectal temperature 42 degrees) enhanced lymphocyte function, proliferative responses to allo-antigens, PHA and Con A increased. Thermal shock was associated with suppression of the spleen cell response. Mice suffering from hyperthermia for 20 min (43-44 degrees) daily during 10, 20 and 30 days showed suppressed T-cell immune response. Normal splenocyte proliferation recovered 40 days after hyperthermia induction.
该研究探讨了脾细胞对丝裂原PHA、Con A或同种异体抗原的增殖反应与热疗效应之间的关系。急性热疗（直肠温度42度）增强了淋巴细胞功能，对同种异体抗原、PHA和Con A的增殖反应增加。热休克与脾细胞反应的抑制有关。在10天、20天和30天期间每天热疗20分钟（43 - 44度）的小鼠表现出T细胞免疫反应受到抑制。热疗诱导后40天，正常脾细胞增殖恢复。
