Wu H, Zhu T B, Du J Y, Hong G X, Sun S Z, Xu X H
Department of Orthopedics, Union Hospital, Tongji Medical University, Wuhan.
Chin Med J (Engl). 1992 Sep;105(9):753-7.
Two kinds of synthetic biomaterial, porous tricalcium phosphate (PTCP) and magnetic porous tricalcium phosphate (MPTCP) ceramic granules were implanted in rat femur. In the period of 4 months, the assessment of serial histological sections, scanning electron microphotographs and quantitative analysis of bone formation in the sections showed that both ceramics are biocompatible and degradable in vivo. More new bone formation occurred in the MPTCP group. Endochondral ossification was seen in both groups. The quantitative analysis in this study is reliable, and may be suitable to the similar experimental models.
将两种合成生物材料，即多孔磷酸三钙（PTCP）和磁性多孔磷酸三钙（MPTCP）陶瓷颗粒植入大鼠股骨。在4个月的时间里，对连续组织学切片的评估、扫描电子显微镜照片以及切片中骨形成的定量分析表明，这两种陶瓷在体内均具有生物相容性且可降解。MPTCP组出现了更多的新骨形成。两组均可见软骨内成骨。本研究中的定量分析是可靠的，可能适用于类似的实验模型。
