Dykes P J, Heggie R
Cutest Systems, Cardiff, UK.
J Wound Care. 2003 Jul;12(7):260-2. doi: 10.12968/jowc.2003.12.7.26567.
The study compared the level of discomfort experienced by healthy volunteers on the removal of a range of adhesive wounds.
This was an open, within subject comparative study of six adhesive dressings in 24 volunteers. The test site was the lower back. Allocation of test materials to the test sites was randomised. The peel force of removal was recorded after 24 hours of application using a device that removed the dressing at a constant speed and angle to the skin surface. The discomfort experienced at each removal was assessed by the subjects themselves using an electronic visual analogue scale.
Overall, Mepilex Border was given a significantly lower discomfort score (p < or = 0.01) by the subjects than the other dressings. There were no clear differences between the five other products tested. Tielle and Allevyn Adhesive had significantly higher (p < or = 0.05) peel force than the other products. Mepilex Border caused less discomfort on removal than Duoderm Extra Thin, Biatain and Versiva, even though the peel force was similar. Tielle and Allevyn had higher peel force, but the levels of discomfort were not significantly higher for these products.
It may be that the level of discomfort experienced by subjects on removal of an adhesive dressing is not entirely dependent on the peel force and that other aspects of the interaction of the skin surface and adhesive play a role.
本研究比较了健康志愿者在去除一系列粘性伤口敷料时所经历的不适程度。
这是一项针对24名志愿者的六种粘性敷料的开放性、受试者自身对照的比较研究。测试部位为下背部。测试材料在测试部位的分配是随机的。使用一种以恒定速度和与皮肤表面成一定角度移除敷料的装置，在敷料应用24小时后记录移除时的剥离力。每次移除时受试者自身使用电子视觉模拟量表评估所经历的不适程度。
总体而言，受试者给予美皮康边框的不适评分显著低于其他敷料（p≤0.01）。其他五种测试产品之间没有明显差异。蒂爱尔和爱立敷粘性敷料的剥离力显著高于其他产品（p≤0.05）。尽管美皮康边框的剥离力与得愈妥超薄型、比亚坦和维思华相似，但在移除时引起的不适比它们少。蒂爱尔和爱立敷具有较高的剥离力，但这些产品的不适程度并没有显著更高。
受试者在去除粘性敷料时所经历的不适程度可能并不完全取决于剥离力，皮肤表面与粘合剂相互作用的其他方面也起作用。
