Wang C X, Wang M, Zhou X
School of Mechanical and Production Engineering, Nanyang Technological University, Nanyang Avenue, Singapore 639798, Singapore.
Biomaterials. 2003 Aug;24(18):3069-77. doi: 10.1016/s0142-9612(03)00154-6.
Bone-like apatite formed on the surface of Ti6Al4V pretreated with NaOH solution after having been immersed in simulated body fluid (SBF), while no apatite formed on the surface of untreated Ti6Al4V. In the present study, electrochemical impedance spectroscopy (EIS) measurement was used to investigate the nucleation and growth of apatite on chemically treated Ti6Al4V immersed in the SBF solution, and the difference between the behaviors of treated and untreated Ti6Al4V. Appropriate equivalent circuit models were constructed to describe the nucleation and growth of apatite, and thin oxide film formed on the surface of untreated Ti6Al4V. It was found that EIS is a useful method for investigating the nucleation and growth of bone-like apatite on Ti6Al4V pretreated with NaOH solution.
在Ti6Al4V浸入模拟体液（SBF）后，用NaOH溶液预处理过的Ti6Al4V表面形成了类骨磷灰石，而未处理的Ti6Al4V表面未形成磷灰石。在本研究中，采用电化学阻抗谱（EIS）测量来研究浸入SBF溶液中的化学处理Ti6Al4V上磷灰石的成核和生长，以及处理和未处理的Ti6Al4V行为之间的差异。构建了合适的等效电路模型来描述磷灰石的成核和生长，以及未处理的Ti6Al4V表面形成的薄氧化膜。结果发现，EIS是研究用NaOH溶液预处理的Ti6Al4V上类骨磷灰石成核和生长的一种有用方法。
