Wang X Y, Noguchi K, Takashima S, Hayashi N, Ogawa S, Seto H
Department of Radiology, Peking University First Hospital, 1000034 Peking, China.
Neuroradiology. 2003 Sep;45(9):640-3. doi: 10.1007/s00234-003-1029-6. Epub 2003 Jul 25.
A patient with mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes (MELAS) was studied with serial diffusion-weighted MRI (DWI) after stroke-like episodes and the apparent diffusion coefficient (ADC) was measured in an infarct-like lesion. In the acute and subacute stages, the affected area gave high signal on DWI and its ADC was much lower than that in a normal control region. In the chronic stage, the ADC became higher than that in normal brain. We therefore suggest that the stroke-like episodes did not cause vasogenic oedema but were related to energy failure and cytotoxic oedema.
对一名患有线粒体肌病、脑病、乳酸性酸中毒和卒中样发作（MELAS）的患者，在卒中样发作后进行了系列扩散加权磁共振成像（DWI）检查，并在梗死样病变中测量了表观扩散系数（ADC）。在急性期和亚急性期，病变区域在DWI上呈高信号，其ADC值远低于正常对照区域。在慢性期，ADC值高于正常脑区。因此，我们认为卒中样发作并非由血管源性水肿引起，而是与能量衰竭和细胞毒性水肿有关。
