Madani Abbas, Fahimi Daryoush, Esfehani Seid Taher, Mohsseni Parvin, Atayee Nematollah, Ahmadi Mahmood, Elmi Fatemeh, Haddadi Marziyeh
Department of Pediatric Nephrology, Children's Hospital Medical Centre, Tehran University of Medical Sciences, Tehran, Iran.
Pediatr Nephrol. 2003 Sep;18(9):925-8. doi: 10.1007/s00467-003-1166-5. Epub 2003 Jul 26.
Glomerular disease constitutes an important part of renal disease. The purpose of this study was to describe and correlate the types of glomerular diseases reported in native kidney biopsy specimens and their clinical presentations in Iranian children. The medical records and pathological diagnoses of patients with glomerular disease whose native kidney biopsy specimens were received by our hospital during a 10-year period were reviewed. In each patient, pathological diagnosis, clinical presentation, age at onset of disease, gender, and presence of nephrotic proteinuria, hematuria, and hypertension, were determined. Minimal-change disease was the most frequent glomerular disease and nephrotic syndrome was the most frequent clinical presentation encountered. For each disease, correlations between the clinical presentation and pathological diagnosis were made. This study describes various glomerular diseases encountered in Iranian children, with their respective clinical presentations.
肾小球疾病是肾脏疾病的重要组成部分。本研究的目的是描述伊朗儿童经肾活检的原发性肾小球疾病的类型及其临床表现，并进行相关性分析。回顾了我院在10年期间接收的原发性肾小球疾病患者的病历和病理诊断。确定了每位患者的病理诊断、临床表现、发病年龄、性别以及是否存在肾病性蛋白尿、血尿和高血压。微小病变病是最常见的肾小球疾病，肾病综合征是最常见的临床表现。针对每种疾病，分析了临床表现与病理诊断之间的相关性。本研究描述了伊朗儿童中遇到的各种肾小球疾病及其各自的临床表现。
