Ginis Harilaos S, Katsanevaki Vikentia J, Pallikaris Ioannis G
University of Crete, School of Medicine, Vardinoyannion Eye Institute, Heraklion, Crete, Greece.
J Refract Surg. 2003 Jul-Aug;19(4):443-8. doi: 10.3928/1081-597X-20030701-11.
The aim of the current study was to control the hypothetical effects of decreased laser energy delivered to the peripheral cornea during phototherapeutic keratectomy (PTK) and provide quantitative calculation of induced low and high order aberrations.
We employed a model eye to simulate the refractive effect of homogeneous laser corneal irradiation, as in PTK, for different laser fluences (range 125 to 225 mJ/cm2) and treatment depths up to 200 microm.
The hyperopic shift induced by the relatively lower energy delivered at the peripheral ablation zone during PTK was proportional to the treatment depth and inversely proportional to the energy fluence. The hyperopic shift calculated using the above ablation parameters was lower compared to previously reported clinical results. Higher order wavefront aberration (total root mean square) changes were of minimal significance for treatment depths up to 200 microm.
After PTK, a hyperopic shift cannot be attributed to the energy delivery method alone. Modification of laser energy delivery algorithms may only minimize PTK-induced hyperopia.
本研究的目的是控制光治疗性角膜切削术(PTK)期间传递到周边角膜的激光能量降低的假设效应,并提供诱导的低阶和高阶像差的定量计算。
我们采用了一个模型眼来模拟均匀激光角膜照射的屈光效应,如在PTK中那样,针对不同的激光能量密度(范围为125至225 mJ/cm²)和高达200微米的治疗深度。
PTK期间周边消融区传递的相对较低能量所引起的远视偏移与治疗深度成正比,与能量密度成反比。使用上述消融参数计算出的远视偏移比先前报道的临床结果要低。对于高达200微米的治疗深度,高阶波前像差(总均方根)变化的意义最小。
PTK后,远视偏移不能仅归因于能量传递方法。激光能量传递算法的修改可能只能将PTK引起的远视最小化。