Hawton Keith, Houston Kelly, Haw Camilla, Townsend Ellen, Harriss Louise
Centre for Suicide Research, Department of Psychiatry, University of Oxford, Warneford Hospital, Oxford OX3 7JX, UK.
Am J Psychiatry. 2003 Aug;160(8):1494-500. doi: 10.1176/appi.ajp.160.8.1494.
The authors compared the characteristics of suicide attempters with and without comorbid psychiatric and personality disorders to identify factors that explain the high suicide risk associated with psychiatric comorbidity.
A representative group of 111 patients who had attempted suicide (72 female and 39 male) was assessed for psychiatric and personality disorders according to ICD-10 criteria. The characteristics of patients with both types of disorder were compared with those of patients without comorbid disorders. A semistructured interview schedule and standardized questionnaires were used to investigate patients' background characteristics, the circumstances of the suicide attempts, psychological characteristics, and outcome after 12-20 months.
Comorbidity of psychiatric and personality disorders was present in 49 patients (44%). More patients with comorbid disorders had made previous suicide attempts (N=41 [84%] versus N=28 [45%]) and repeated attempts during the follow-up period (N=25 [51%] versus N=9 [15%]). Differences in precipitants and motives for the index episode were also found: patients with comorbid disorders were more depressed and hopeless, reported more episodes of aggression, were more impulsive, and had lower self-esteem and poorer problem-solving skills. Differences in self-esteem and problem-solving skills distinguished between the groups in a stepwise discriminant function analysis. More of the patients with comorbid disorders reported not being loved by their parents and parental suicidal behavior.
Suicide attempters with comorbid psychiatric and personality disorders show marked differences from those without both of these disorders. Comorbidity may contribute to greater suicide risk. Some of the characteristics of patients with comorbid disorders pose major clinical challenges that should be addressed in an effort to reduce suicide risk.
作者比较了伴有和不伴有共病性精神障碍及人格障碍的自杀未遂者的特征,以确定能解释与精神障碍共病相关的高自杀风险的因素。
根据国际疾病分类第十版(ICD - 10)标准,对111名有自杀未遂经历的患者(72名女性和39名男性)进行了代表性抽样评估,以确定其是否患有精神障碍及人格障碍。将患有这两种障碍的患者的特征与无共病障碍的患者的特征进行比较。采用半结构化访谈提纲和标准化问卷来调查患者的背景特征、自杀未遂情况、心理特征以及12 - 20个月后的结局。
49名患者(44%)存在精神障碍与人格障碍共病。更多患有共病障碍的患者曾有过自杀未遂经历(41例[84%]对28例[45%]),且在随访期间有多次自杀未遂(25例[51%]对9例[15%])。在此次自杀事件的诱发因素和动机方面也发现了差异:患有共病障碍的患者更抑郁、绝望,报告有更多攻击性行为发作,更冲动,自尊水平更低且解决问题的能力更差。在逐步判别函数分析中,自尊和解决问题能力的差异区分了两组。更多患有共病障碍的患者报告未得到父母的关爱以及父母有自杀行为。
伴有共病性精神障碍及人格障碍的自杀未遂者与无这两种障碍的自杀未遂者表现出明显差异。共病可能导致更高的自杀风险。患有共病障碍的患者的一些特征带来了重大临床挑战,应加以应对以降低自杀风险。