Baylé Franck J, Caci Hervé, Millet Bruno, Richa Sami, Olié Jean-Pierre
Institut National de la Santé et de Recherche Médicale, E0117, Univesité Paris V et Service Hospitalo-Universitaire de Santé Mentale et de Thérapeutique, Paris, France.
Am J Psychiatry. 2003 Aug;160(8):1509-13. doi: 10.1176/appi.ajp.160.8.1509.
This study compared patients with kleptomania, patients with alcohol abuse or dependence, and psychiatric patients without impulse-control disorders or substance-related disorders on several key psychopathological dimensions. In addition, the comorbidity of kleptomania with other psychiatric disorders was examined.
Eleven patients with kleptomania recruited over a cumulative 2-year period and 60 patients with alcohol abuse or dependence and 29 psychiatric comparison patients recruited over a consecutive 6-month period participated in structured clinical interviews to determine the presence of impulse-control and substance-related disorders and of other psychiatric disorders that were comorbid with kleptomania. Psychopathological dimensions were measured with the Barratt Impulsiveness Scale, the Sensation Seeking Scale, the Montgomery-Asberg Depression Rating Scale, and the anxiety and depression subscales of the Hospital Anxiety and Depression Scale.
Significant group effects were found for the Barratt Impulsiveness Scale total and cognitive impulsivity scores, with the patients with kleptomania having higher impulsivity scores than the other groups. Significant group differences were found on the Sensation Seeking Scale total and disinhibition scores. No significant group effects were found for the mood and anxiety measures. Patients with kleptomania had high rates of comorbid psychiatric disorders, particularly mood disorders, other impulse-control disorders, and substance abuse or dependence (mainly nicotine dependence).
Kleptomania presented a specific psychopathological profile that distinguished patients with this disorder from patients with alcohol abuse or dependence and other psychiatric comparison patients. Impulsivity was the major psychopathological feature of kleptomania. A link between kleptomania and affective disorder was supported by the high rate of comorbid affective disorders in patients with kleptomania and a specific pattern of variation in the two conditions over time. Further prospective studies are needed to confirm this pattern. Because kleptomania is characterized by a low rate of comorbid substance-related disorders other than nicotine dependence and by severe psychopathology, it could be an appropriate disorder in which to study the information processes and psychobiology underlying impulsivity.
本研究在几个关键的精神病理学维度上,对盗窃癖患者、酒精滥用或依赖患者以及无冲动控制障碍或物质相关障碍的精神科患者进行了比较。此外,还对盗窃癖与其他精神障碍的共病情况进行了检查。
在累计2年的时间里招募了11名盗窃癖患者,在连续6个月的时间里招募了60名酒精滥用或依赖患者以及29名精神科对照患者,他们参与了结构化临床访谈,以确定冲动控制障碍、物质相关障碍以及与盗窃癖共病的其他精神障碍的存在情况。使用巴拉特冲动性量表、感觉寻求量表、蒙哥马利-阿斯伯格抑郁评定量表以及医院焦虑抑郁量表的焦虑和抑郁分量表来测量精神病理学维度。
在巴拉特冲动性量表总分和认知冲动性得分上发现了显著的组间效应,盗窃癖患者的冲动性得分高于其他组。在感觉寻求量表总分和去抑制得分上发现了显著的组间差异。在情绪和焦虑测量方面未发现显著的组间效应。盗窃癖患者共病精神障碍的发生率较高,尤其是情绪障碍、其他冲动控制障碍以及物质滥用或依赖(主要是尼古丁依赖)。
盗窃癖呈现出一种特定的精神病理学特征,将该障碍患者与酒精滥用或依赖患者以及其他精神科对照患者区分开来。冲动性是盗窃癖的主要精神病理学特征。盗窃癖患者中情感障碍的高共病率以及这两种情况随时间变化的特定模式支持了盗窃癖与情感障碍之间的联系。需要进一步的前瞻性研究来证实这种模式。由于盗窃癖的特征是除尼古丁依赖外与物质相关障碍的共病率较低且精神病理学严重,它可能是研究冲动性背后的信息处理过程和心理生物学的合适障碍。