Greer Ian A
University of Glasgow, Glasgow Royal Infirmary, 10 Alexandra Parade, Glasgow G3I 2ER, Scotland, UK.
Curr Hematol Rep. 2002 Sep;1(1):56-62.
Pulmonary thromboembolism is a major cause of maternal death in the developed world. Underlying this condition is the problem of deep venous thrombosis. These problems often reflect an underlying hypercoagulable state. Growing evidence implicates congenital and acquired thrombophilias in the pathophysiologic processes underlying not only venous thrombosis, but also miscarriage, intrauterine growth restriction, and preeclampsia, raising new possibilities for intervention.
在发达国家，肺血栓栓塞症是孕产妇死亡的主要原因。这种情况的根本问题是深静脉血栓形成。这些问题往往反映出潜在的高凝状态。越来越多的证据表明，先天性和获得性血栓形成倾向不仅在静脉血栓形成的病理生理过程中起作用，而且在流产、胎儿生长受限和先兆子痫中也起作用，这为干预提供了新的可能性。
