Davenport Robertson D
Department of Pathology, University Hospital 2G33/0054, 1500 E. Medical Center Drive, Ann Arbor, MI 48109-0054, USA.
Curr Hematol Rep. 2002 Nov;1(2):142-8.
The appropriate threshold for administration of red blood cell transfusion is the subject of controversy. Recently, several prospective randomized clinical trials have compared restrictive and liberal transfusion regimens in the settings of critical care and surgery. In addition, several large cohort studies have provided information on associations between anemia, transfusion, and clinical outcomes. Taken together, these studies generally support conservative red blood cell transfusion strategies.
红细胞输注的合适阈值是一个存在争议的话题。最近,几项前瞻性随机临床试验在重症监护和手术背景下比较了限制性和宽松输血方案。此外,几项大型队列研究提供了关于贫血、输血与临床结局之间关联的信息。综合来看,这些研究总体上支持保守的红细胞输血策略。