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人类免疫缺陷病毒阳性糖尿病患者糖化血红蛋白A1C测量不准确

Inaccurate glycosylated hemoglobin A1C measurements in human immunodeficiency virus-positive patients with diabetes mellitus.

作者信息

Polgreen Philip M, Putz Darcy, Stapleton Jack T

机构信息

Department of Internal Medicine and Research, Iowa City Veterans Administration Medical Center and University of Iowa, Iowa City, IA, USA.

出版信息

Clin Infect Dis. 2003 Aug 15;37(4):e53-6. doi: 10.1086/376633. Epub 2003 Jul 30.

DOI:10.1086/376633
PMID:12905153
Abstract

Persistent differences in blood glucose and serum glycosylated hemoglobin (HbA1C) measurements were observed in 4 human immunodeficiency virus-positive patients with diabetes mellitus, all of whom were taking drugs associated with hemolysis, which interferes with the reliability of HbA1C levels. Determination of fructosamine levels was a more accurate alternative for measuring average glycemic control in these patients.

摘要

在4例合并糖尿病的人类免疫缺陷病毒阳性患者中观察到血糖和血清糖化血红蛋白(HbA1C)测量值存在持续差异,所有这些患者都在服用与溶血相关的药物,这会干扰HbA1C水平的可靠性。对于这些患者,测定果糖胺水平是测量平均血糖控制情况的更准确替代方法。

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