Daubin Vincent, Moran Nancy A, Ochman Howard
Department of Biochemistry and Molecular Biophysics, University of Arizona, Tucson, AZ, 85721, USA.
Science. 2003 Aug 8;301(5634):829-32. doi: 10.1126/science.1086568.
Gene acquisition is an ongoing process in many bacterial genomes, contributing to adaptation and ecological diversification. Lateral gene transfer is considered the primary explanation for discordance among gene phylogenies and as an obstacle to reconstructing the tree of life. We measured the extent of phylogenetic conflict and alien-gene acquisition within quartets of sequenced genomes. Although comparisons of complete gene inventories indicate appreciable gain and loss of genes, orthologs available for phylogenetic reconstruction are consistent with a single tree.
基因获取是许多细菌基因组中持续进行的过程，有助于适应和生态多样化。横向基因转移被认为是基因系统发育不一致的主要原因，也是重建生命之树的障碍。我们测量了已测序基因组四重奏中系统发育冲突和外源基因获取的程度。尽管对完整基因库的比较表明基因有明显的增减，但可用于系统发育重建的直系同源基因与单一的树状图是一致的。
