Jäger M D M, Hintermayr M, Bottlender R, Strauss A, Möller H-J
Psychiatrische Klinik der Ludwig-Maximilians-Universität, Nussbaumstr. 7, 80336 Munich, Germany.
Eur Arch Psychiatry Clin Neurosci. 2003 Aug;253(4):209-15. doi: 10.1007/s00406-003-0435-4.
The aim of the present study was to investigate course and outcome of acute and transient psychotic disorders (ATPD).
A sample of 73 first-hospitalized patients was evaluated after three to seven years in order to determine the frequency of relapses and to assess social adjustment.
Forty-two percent experienced no relapse, 46% experienced relapses without developing marked deficits in social adjustment and 12% had relapses associated with a severe social impairment. At discharge from first hospitalization the last group was distinguishable from the other two with respect to negative and depressive symptoms as well as the total score of the Strauss-Carpenter scale.
Only a minority of first-hospitalized patients with ATPD develop a severe social impairment after three to seven years. This subgroup, however, is not compatible with the concept of a "transient" psychotic disturbance, but rather with an early manifestation of a chronic schizophrenic disorder.
本研究旨在调查急性短暂性精神病性障碍（ATPD）的病程及转归。
对73例首次住院患者样本在三至七年之后进行评估，以确定复发频率并评估社会适应情况。
42%的患者未复发，46%的患者复发但未出现明显的社会适应缺陷，12%的患者复发且伴有严重的社会功能损害。首次住院出院时，最后一组在阴性和抑郁症状以及施特劳斯 - 卡彭特量表总分方面与其他两组有所不同。
首次住院的ATPD患者中，只有少数在三至七年之后会出现严重的社会功能损害。然而，这一亚组不符合“短暂性”精神病性障碍的概念，而更符合慢性精神分裂症障碍的早期表现。
