Massenti M F, Intonazzo V, Vinciguerra M, Scavuzzo A, Potenzano S, Iannitto E, Lampiasi A M
Dip. di Igiene e Microbiologia G. D'Alessandro, Università degli Studi di Palermo.
Ann Ig. 2003 May-Jun;15(3):183-9.
Monoclonal gammopathies (GM) are divided into clinically manifest and asymptomatic syndromes. In the last 20 years, the prevalence of GM in industrialized Countries is more than doubled. In order to verify the prevalence of these forms in Western Sicily, at University General Hospital of Palermo an epidemiologic inquiry was made to check the presence of GM as fortuitous event during routine analyses; from March 2000 to March 2001 it was found a prevalence of 0.89% (196 cases on 22100 analysed). Average age was 67.5, with 58.2% men and 41.8% women from different Departments of University General Hospital. The finding of a monoclonal component must be considered an important laboratory datum to observe with time by not invasive laboratory examinations (high-resolution serum-protein electrophoresis and immunofixation).
单克隆丙种球蛋白病（GM）分为有临床表现和无症状综合征。在过去20年中，工业化国家GM的患病率增加了一倍多。为了核实西西里岛西部这些类型疾病的患病率，在巴勒莫大学综合医院进行了一项流行病学调查，以检查在常规分析期间作为偶然事件出现的GM；2000年3月至2001年3月期间，发现患病率为0.89%（22100例分析病例中有196例）。平均年龄为67.5岁，来自大学综合医院不同科室，男性占58.2%，女性占41.8%。单克隆成分的发现必须被视为一个重要的实验室数据，通过非侵入性实验室检查（高分辨率血清蛋白电泳和免疫固定）随时间观察。
