Li Kuo-Bin
Bioinformatics Institute, 30 Medical Drive, Singapore 117609, Republic of Singapore.
Bioinformatics. 2003 Aug 12;19(12):1585-6. doi: 10.1093/bioinformatics/btg192.
ClustalW is a tool for aligning multiple protein or nucleotide sequences. The alignment is achieved via three steps: pairwise alignment, guide-tree generation and progressive alignment. ClustalW-MPI is a distributed and parallel implementation of ClustalW. All three steps have been parallelized to reduce the execution time. The software uses a message-passing library called MPI (Message Passing Interface) and runs on distributed workstation clusters as well as on traditional parallel computers.
ClustalW是一种用于比对多个蛋白质或核苷酸序列的工具。比对通过三个步骤实现：两两比对、引导树生成和渐进比对。ClustalW-MPI是ClustalW的分布式并行实现。所有这三个步骤都已并行化以减少执行时间。该软件使用一种名为MPI（消息传递接口）的消息传递库，并可在分布式工作站集群以及传统并行计算机上运行。
