Inappropriate ileal conservation of bile acids in cholestatic liver disease: homeostasis gone awry.
作者信息
Hofmann A F
机构信息
Division of Gastroenterology, Department of Medicine, University of California, San Diego 92093-0813, USA.
出版信息
Gut. 2003 Sep;52(9):1239-41. doi: 10.1136/gut.52.9.1239.
Abstract
摘要
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本文引用的文献
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Mol Cell. 2003 Apr;11(4):1093-100. doi: 10.1016/s1097-2765(03)00112-6.
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A chemical, genetic, and structural analysis of the nuclear bile acid receptor FXR.核胆汁酸受体FXR的化学、遗传及结构分析
Mol Cell. 2003 Apr;11(4):1079-92. doi: 10.1016/s1097-2765(03)00104-7.
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Inhibition of both the apical sodium-dependent bile acid transporter and HMG-CoA reductase markedly enhances the clearance of LDL apoB.抑制顶端钠依赖性胆汁酸转运蛋白和HMG-CoA还原酶均能显著增强低密度脂蛋白载脂蛋白B的清除率。
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