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法国儿童群体中麻疹发病率的低估情况。

Underestimation of the incidence of measles in a population of French children.

作者信息

Gendrel D, Chemillier-Truong M, Rodrique D, Raymond J, Bosco O, Saliou P, Lebon P

机构信息

Département de Pédiatrie, Hôpital Saint Vincent de Paul, Paris, France.

出版信息

Eur J Clin Microbiol Infect Dis. 1992 Dec;11(12):1156-7. doi: 10.1007/BF01961134.

DOI:10.1007/BF01961134
PMID:1291311
Abstract

Data on titres of specific antibodies against measles virus and information given by families and physicians were analysed in 133 vaccinated and 117 unvaccinated children. Only 2 of the 133 vaccinated children reported a history of measles, while 131 had detectable levels of antibodies. Measles antibodies were detected in 102 (87.2%) of the unvaccinated children, but a history of measles diagnosed clinically by a physician was reported in only 42 of them. These findings suggest that subclinical cases of measles are possible and contribute to the high circulation of the measles virus in the child population in France.

摘要

对133名接种过疫苗和117名未接种疫苗的儿童,分析了其针对麻疹病毒的特异性抗体滴度数据以及家庭和医生提供的信息。133名接种过疫苗的儿童中,只有2名报告有麻疹病史,而131名有可检测到的抗体水平。在102名(87.2%)未接种疫苗的儿童中检测到麻疹抗体,但其中只有42名儿童有医生临床诊断的麻疹病史。这些发现表明,麻疹亚临床病例是可能存在的,并且促成了法国儿童群体中麻疹病毒的高传播率。

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