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从煮过的大蒜（大蒜）中分离和鉴定氧化犬红细胞的2-丙烯基硫代硫酸钠。

Isolation and identification of sodium 2-propenyl thiosulfate from boiled garlic (Allium sativum) that oxidizes canine erythrocytes.

作者信息

Yamato Osamu, Sugiyama Yuko, Matsuura Hideyuki, Lee Keun-Woo, Goto Koichi, Hossain Mohammad Alamgir, Maede Yoshimitsu, Yoshihara Teruhiko

机构信息

Laboratory of Internal Medicine, Department of Veterinary Clinical Sciences, Graduate School of Veterinary Medicine, Hokkaido University, Sapporo, Japan.

出版信息

Biosci Biotechnol Biochem. 2003 Jul;67(7):1594-6. doi: 10.1271/bbb.67.1594.

DOI:10.1271/bbb.67.1594
PMID:12913309
Abstract

Sodium 2-propenyl thiosulfate was identified in boiled garlic (Allium sativum). When canine erythrocytes were incubated with sodium 2-propenyl thiosulfate, the methemoglobin concentration and Heinz body percentage in erythrocytes were both increased, indicating that the compound induced oxidative damage in canine erythrocytes. It seems that this compound is one of the causative agents of garlic-induced hemolysis in dogs.

摘要

在煮过的大蒜（葱属植物大蒜）中鉴定出了2-丙烯基硫代硫酸钠。当犬红细胞与2-丙烯基硫代硫酸钠一起孵育时，红细胞中的高铁血红蛋白浓度和海因茨小体百分比均增加，表明该化合物在犬红细胞中诱导了氧化损伤。看来这种化合物是大蒜引起犬溶血的致病因素之一。

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引用本文的文献

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Radioprotective effect of alk(en)yl thiosulfates derived from allium vegetables against DNA damage caused by X-ray irradiation in cultured cells: antiradiation potential of onions and garlic.葱属蔬菜衍生的烷基（烯基）硫代硫酸盐对培养细胞中X射线辐射引起的DNA损伤的辐射防护作用：洋葱和大蒜的抗辐射潜力。
ScientificWorldJournal. 2012;2012:846750. doi: 10.1100/2012/846750. Epub 2012 Jul 31.