Eckardt André, Fokas Konstantinos
Department of Oral and Maxillofacial Surgery, Hannover Medical University, Carl-Neuberg-Strasse 1, Hannover 30625, Germany.
J Craniomaxillofac Surg. 2003 Aug;31(4):197-201. doi: 10.1016/s1010-5182(03)00039-8.
Microvascular free tissue transfer has become a significant factor in the reconstruction of head and neck cancer patients. Various donor sites are available to enable anatomical and functional repair of a defect.
All free vascularized tissue transfers performed during the period from March 1982 to September 2000 were retrieved from this hospital's database and analysed with regard to the surgical defect, chosen donor site and complications.
During the 18-year period a total of 1,164 patients with head and neck cancer were treated in this institution. A total of 500 free-flap reconstructions were performed for 479 patients. In the majority of patients (n = 451) reconstruction was indicated following ablative tumour surgery. With regard to donor site selection, the first choice of free jejunum was used in 181 patients, followed by the radial forearm flap in 140 patients. Among the 500 free-flap reconstructions, a total flap loss rate of 6% was observed. Patient age (p = 0.004) and tobacco use (p = 0.043) were significant risk factors for complications overall, whereas patient age (p = 0.021) and operating time (p = 0.043) were significantly correlated with local complications.
Immediate repair of head and neck defects using free tissue transfer is a successful and reliable method and is becoming the gold standard at many institutions. The complication rate is low once experience with these techniques has been acquired.
微血管游离组织移植已成为头颈癌患者重建的重要因素。有多种供区可供选择,以实现缺损的解剖和功能修复。
从本院数据库中检索1982年3月至2000年9月期间进行的所有游离血管化组织移植,并就手术缺损、所选供区和并发症进行分析。
在这18年期间,该机构共治疗了1164名头颈癌患者。共为479名患者进行了500次游离皮瓣重建。在大多数患者(n = 451)中,重建是在肿瘤切除术后进行的。关于供区选择,181名患者首选游离空肠,其次是140名患者选择桡侧前臂皮瓣。在500次游离皮瓣重建中,观察到总的皮瓣丢失率为6%。患者年龄(p = 0.004)和吸烟(p = 0.043)是总体并发症的重要危险因素,而患者年龄(p = 0.021)和手术时间(p = 0.043)与局部并发症显著相关。
使用游离组织移植立即修复头颈缺损是一种成功且可靠的方法,正在成为许多机构的金标准。一旦掌握了这些技术,并发症发生率就会很低。