Bhatt H V, Panchal G M
Division of Neurobehavioural Toxicology, National Institute of Occupational Health, Meghani Nagar, Ahmedabad.
Indian J Physiol Pharmacol. 1992 Oct;36(4):270-2.
Impact of chronic formaldehyde exposure in respect of route on behaviour was studied. Preconditioned (environmental) male albino rats (340-400 g) in 3 groups (n = 5) under 60 days oral and systemic exposure to 10 mg/kg/day HCHO were examined for their behavioural performance (i.e. short term memory) in Cook's apparatus. Twenty percent rats settled in grade III (unconditioned avoidance response) in the i.p. (i.e. systemic group) whereas in oral fed (HCHO route in drinking water) rats, 60% settled in grade II (conditioned avoidance response) at the end of sixty days.
研究了慢性甲醛暴露途径对行为的影响。对3组（每组n = 5）经过预处理（适应环境）的雄性白化大鼠（体重340 - 400克），进行为期60天的口服和全身暴露，剂量为10毫克/千克/天的甲醛，然后在库克装置中检测它们的行为表现（即短期记忆）。腹腔注射组（即全身暴露组）中有20%的大鼠达到III级（非条件回避反应），而口服组（通过饮用水摄入甲醛）的大鼠在60天结束时，有60%达到II级（条件回避反应）。
