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Halothane, a novel solvent for the preparation of liposomes containing 2-4'-amino-3'-methylphenyl benzothiazole (AMPB), an anticancer drug: a technical note.氟烷，一种用于制备含有抗癌药物2-4'-氨基-3'-甲基苯基苯并噻唑（AMPB）的脂质体的新型溶剂：技术说明。
AAPS PharmSciTech. 2003;4(2):E20. doi: 10.1208/pt040220.
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Liposome formulation of NSC-639829 using halothane as a solvent: a technical note.以氟烷为溶剂的NSC-639829脂质体制剂：技术说明
AAPS PharmSciTech. 2003 Oct 15;4(4):E52. doi: 10.1208/pt040452.
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The discovery of the potent and selective antitumour agent 2-(4-amino-3-methylphenyl)benzothiazole (DF 203) and related compounds.强效选择性抗肿瘤药物2-（4-氨基-3-甲基苯基）苯并噻唑（DF 203）及相关化合物的发现。
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Cancer Res. 2000 Sep 15;60(18):5196-203.
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The development of the antitumour benzothiazole prodrug, Phortress, as a clinical candidate.抗肿瘤苯并噻唑前药福司曲星作为临床候选药物的研发。
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Fluorinated 2-(4-amino-3-methylphenyl)benzothiazoles induce CYP1A1 expression, become metabolized, and bind to macromolecules in sensitive human cancer cells.氟化2-(4-氨基-3-甲基苯基)苯并噻唑可诱导CYP1A1表达，发生代谢，并与敏感人类癌细胞中的大分子结合。
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Drug Discov Today. 2012 Feb;17(3-4):160-6. doi: 10.1016/j.drudis.2011.09.015. Epub 2011 Sep 29.

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Nanoliposomes for encapsulation and delivery of the potential antitumoral methyl 6-methoxy-3-(4-methoxyphenyl)-1H-indole-2-carboxylate.纳米脂质体用于封装和递送潜在的抗肿瘤甲基 6-甲氧基-3-(4-甲氧基苯基)-1H-吲哚-2-羧酸酯。
Nanoscale Res Lett. 2011 Aug 3;6(1):482. doi: 10.1186/1556-276X-6-482.
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Design and development of multivesicular liposomal depot delivery system for controlled systemic delivery of acyclovir sodium.用于阿昔洛韦钠控释全身给药的多囊泡脂质体长效注射系统的设计与开发
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3
Liposome formulation of NSC-639829 using halothane as a solvent: a technical note.以氟烷为溶剂的NSC-639829脂质体制剂：技术说明
AAPS PharmSciTech. 2003 Oct 15;4(4):E52. doi: 10.1208/pt040452.

本文引用的文献

1
Chloroform in the environment: occurrence, sources, sinks and effects.环境中的氯仿：存在、来源、汇及影响。
Chemosphere. 2003 Mar;50(10):1291-308. doi: 10.1016/s0045-6535(02)00697-5.
2
Pharmacokinetic comparison of intravenous carbendazim and remote loaded carbendazim liposomes in nude mice.静脉注射多菌灵与远程载入多菌灵脂质体在裸鼠体内的药代动力学比较。
J Pharm Biomed Anal. 2002 Apr 1;28(1):65-72. doi: 10.1016/s0731-7085(01)00702-6.
3
Theoretical considerations of RES-avoiding liposomes: Molecular mechanics and chemistry of liposome interactions.避开网状内皮系统的脂质体的理论思考：脂质体相互作用的分子力学与化学
Adv Drug Deliv Rev. 1998 Jun 8;32(1-2):119-138. doi: 10.1016/s0169-409x(97)00135-x.
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Ligand-targeted liposomes.配体靶向脂质体
Adv Drug Deliv Rev. 1998 Feb 2;29(3):249-271. doi: 10.1016/s0169-409x(97)00083-5.
5
A comprehensive approach for integration of toxicity and cancer risk assessments.一种整合毒性和癌症风险评估的综合方法。
Regul Toxicol Pharmacol. 1999 Feb;29(1):23-36. doi: 10.1006/rtph.1998.1273.
6
Patterns of chloroform-induced regenerative cell proliferation in BDF1 mice correlate with organ specificity and dose-response of tumor formation.BDF1小鼠中氯仿诱导的再生细胞增殖模式与器官特异性及肿瘤形成的剂量反应相关。
Carcinogenesis. 1998 Jan;19(1):187-93. doi: 10.1093/carcin/19.1.187.
7
Structural studies on bioactive compounds. 23. Synthesis of polyhydroxylated 2-phenylbenzothiazoles and a comparison of their cytotoxicities and pharmacological properties with genistein and quercetin.生物活性化合物的结构研究。23. 多羟基化2-苯基苯并噻唑的合成及其与染料木黄酮和槲皮素的细胞毒性和药理特性比较。
J Med Chem. 1994 May 27;37(11):1689-95. doi: 10.1021/jm00037a020.
8
Delivery of liposomes into cultured KB cells via folate receptor-mediated endocytosis.通过叶酸受体介导的内吞作用将脂质体递送至培养的KB细胞中。
J Biol Chem. 1994 Feb 4;269(5):3198-204.
9
A novel method for encapsulation of macromolecules in liposomes.一种将大分子包裹于脂质体中的新方法。
Biochim Biophys Acta. 1985 Jun 11;816(1):1-8. doi: 10.1016/0005-2736(85)90386-4.

Halothane, a novel solvent for the preparation of liposomes containing 2-4'-amino-3'-methylphenyl benzothiazole (AMPB), an anticancer drug: a technical note.

作者信息

Ran Yingqing, Yalkowsky Samuel H

机构信息

College of Pharmacy, University of Arizona, Tucson, AZ 85721, USA.

出版信息

AAPS PharmSciTech. 2003;4(2):E20. doi: 10.1208/pt040220.

DOI:10.1208/pt040220
PMID:12916902
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2750598/
Abstract
摘要